Top 40 InterPro Domains in the Ensembl Database

No.

Interpro name	Number of genes	Number of Ensembl hits	No.	Interpro name	Number of genes	Number of Ensembl hits
1	IPR000694 Proline-rich region	541	4217	21	IPR001304 C-type lectin	54	351
2	IPR000276 Rhodopsin-like GPCR superfamily	374	5349	22	IPR003598 Immunoglobulin subtype 2	53	657
3	IPR000719 Protein kinase	323	3439	23	IPR000048 IQ calmodulin-binding region	52	908
4	IPR001680 WD-40 repeat	154	1979	24	IPR001128 Cytochrome P450	51	860
5	IPR000504 RNA-binding region RNP-1 (RNA recognition motif)	133	868	25	IPR000742 EGF-like, type 3	50	1109
6	IPR003596 Immunoglobulin V-set, subgroup	130	1630	26	IPR001254 Peptidase S1 and S6, chymotrypsin/Hap	50	376
7	IPR001841 Zinc finger, RING-type	108	678	27	IPR001356 Homeobox	49	336
8	IPR001781 LIM, zinc-binding	99	3407	28	IPR002126 Cadherin	48	1200
9	IPR000533 Tropomyosin	97	580	29	IPR001664 Intermediate filament protein	47	321
10	IPR000008 C2 calcium-dependent membrane targeting	94	1114	30	IPR000219 DH	47	450
11	IPR002110 Ankyrin	93	1396	31	IPR007087 Zinc finger, C2H2-type	47	665
12	IPR001806 Ras GTPase	93	803	32	IPR000198 RhoGAP	46	338
13	IPR000210 BTB	89	1360	33	IPR000104 Antifreeze protein, type I	45	433
14	IPR001611 Leucine-rich repeat	87	1001	34	IPR001478 PDZ/DHR/GLGF	45	352
15	IPR001909 KRAB box	83	2771	35	IPR000315 Zinc finger, B-box	44	612
16	IPR002048 Calcium-binding EF-hand	82	524	36	IPR001993 Mitochondrial substrate carrier	42	509
17	IPR000047 Helix-turn-helix motif, lambda-like repressor	81	865	37	IPR002198 Short-chain dehydrogenase/reductase SDR	41	456
18	IPR000152 Aspartic acid and asparagine hydroxylation site	70	4587	38	IPR000108 Neutrophil cytosol factor 2	41	792
19	IPR007086 Zinc finger, C2H2-subtype	66	1774	39	IPR001092 Basic helix-loop-helix dimerisation region bHLH	41	165
20	IPR001440 Tetratricopeptide TPR_1	64	1035	40	IPR001849 Pleckstrin-like	39	147

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