Top 40 InterPro Domains in the Ensembl Database

No.

Interpro name	Number of genes	Number of Ensembl hits	No.	Interpro name	Number of genes	Number of Ensembl hits
1	IPR000104 Antifreeze protein, type I	413	10543	21	IPR004119 Protein of unknown function DUF227	53	204
2	IPR000694 Proline-rich region	401	4473	22	IPR007087 Zinc finger, C2H2-type	53	723
3	IPR001254 Peptidase S1 and S6, chymotrypsin/Hap	233	2124	23	IPR001440 Tetratricopeptide TPR-1	47	1254
4	IPR000719 Protein kinase, core	163	5359	24	IPR001092 Basic helix-loop-helix dimerisation region bHLH	46	303
5	IPR001680 WD40 repeat	146	3519	25	IPR007086 Zinc finger, C2H2-subtype	45	1269
6	IPR000504 RNA recognition motif, RNP-1	120	2125	26	IPR001993 Mitochondrial substrate carrier	45	1045
7	IPR000618 Insect cuticle protein	104	683	27	IPR000008 C2 calcium-dependent membrane targeting	44	1552
8	IPR001128 Cytochrome P450	90	2096	28	IPR002110 Ankyrin	44	1293
9	IPR006617 Protein of unknown function DM8	83	89	29	IPR001781 Zinc finger, LIM-type	43	1845
10	IPR001841 Zinc finger, RING-type	81	688	30	IPR013604 7TM chemoreceptor	43	53
11	IPR000276 Rhodopsin-like GPCR superfamily	77	1823	31	IPR002198 Short-chain dehydrogenase/reductase SDR	42	814
12	IPR002557 Chitin binding protein, peritrophin-A	70	901	32	IPR000480 Glutelin	42	532
13	IPR000533 Tropomyosin	70	797	33	IPR000215 Protease inhibitor I4, serpin	40	435
14	IPR000047 Helix-turn-helix motif, lambda-like repressor	70	1617	34	IPR000073 Alpha/beta hydrolase fold-1	40	222
15	IPR001806 Ras GTPase	68	1424	35	IPR006170 Pheromone/general odorant binding protein, PBP/GOBP	39	121
16	IPR001611 Leucine-rich repeat	64	1148	36	IPR002952 Eggshell protein	38	276
17	IPR002048 Calcium-binding EF-hand	58	854	37	IPR003656 Zinc finger, BED-type predicted	38	1092
18	IPR000210 BTB/POZ-like	58	1844	38	IPR004045 Glutathione S-transferase, N-terminal	36	181
19	IPR004117 Olfactory receptor, Drosophila	56	72	39	IPR000637 HMG-I and HMG-Y, DNA-binding	36	718
20	IPR003596 Immunoglobulin V-set, subgroup	54	6617	40	IPR003593 AAA+ ATPase, core	36	134

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